Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 755
interventional 549
Observational 202
Registry 4

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 299
Biological 36
Device 33
Procedure 33
Drug|Other 24
Drug|placebo 20
Other 20
Behavioral 15
Dietary Supplement 11
Dietary Supplement|placebo 8
Drug|Procedure 7
Biological|Drug 6
Device|Drug 4
Biological|Other 3
Genetic 3
Biological|placebo 2
Biological|Procedure 2
Diagnostic Test 2
Dietary Supplement|Drug 2
Dietary Supplement|Other 2
Other|placebo 2
Radiation 2
Behavioral|Other 1
Biological|Device 1
Biological|Drug|Other 1
Biological|Drug|placebo 1
Combination Product 1
Combination Product|placebo 1
Device|Drug|Procedure 1
Device|placebo 1
Diagnostic Test|Drug|Other 1
Diagnostic Test|Procedure 1
Dietary Supplement|Drug|placebo 1
Drug|Radiation 1
placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 234
NA 50
China 23
Canada 19
Austria 18
France 16
Japan 14
Germany 13
Korea, Republic of 11
Italy 10
Switzerland 10
United Kingdom 10
United States|Canada 7
Australia 6
Spain 5
Brazil 4
United States|Puerto Rico 4
United States|United Kingdom 3
Egypt 2
Greece 2
Hungary 2
Israel 2
Nepal 2
Netherlands 2
Norway 2
Sweden 2
Turkey 2
United States|Australia 2
United States|Israel 2
Argentina 1
Argentina|Australia|Austria|Belgium|Brazil|Colombia|Czech Republic|France|Germany|Hungary|India|Israel|Italy|Japan|Korea, Republic of|Latvia|Mexico|Netherlands|Poland|Portugal|Singapore|Slovakia|Spain|Sweden|Switzerland|United Kingdom 1
Argentina|Austria|Canada|Colombia|Czechia|Finland|France|Germany|Greece|Guatemala|Hungary|Ireland|Italy|Lithuania|Mexico|Netherlands|Panama|Portugal|Slovakia|Spain|Sweden|Switzerland|Turkey|United Kingdom 1
Australia|Belgium|Germany|Hungary|Israel|Netherlands|Portugal|Spain|Turkey|United Kingdom 1
Austria|Belgium|Denmark|France|Germany|Netherlands|Norway|Portugal|Sweden|Switzerland 1
Austria|Canada|Czechia|France|Germany|Hungary|Italy|Lithuania|Poland|Portugal|Slovakia|Spain|Switzerland|United Kingdom 1
Austria|Czech Republic|Germany|Italy|United Kingdom 1
Austria|Germany|Hungary 1
Belgium 1
Belgium|Chile|Croatia|Denmark|Egypt|Germany|Hungary|India|Israel|Italy|Korea, Republic of|Portugal|Russian Federation|Slovakia|Slovenia|Spain|Switzerland|Turkey|United Kingdom 1
Belgium|Netherlands 1
Canada|Hong Kong 1
Chile 1
Colombia 1
Finland 1
France|Germany|Italy 1
Germany|United Kingdom 1
Hong Kong|Japan|Korea, Republic of|Malaysia|Singapore|Taiwan|Thailand 1
Hungary|Australia|Canada|France|Germany|Italy|Spain|United Kingdom 1
Hungary|United States|Germany|Poland 1
Iran, Islamic Republic of 1
Israel|Korea, Republic of|Malaysia|Philippines|Singapore|Taiwan|Thailand 1
Japan|United States|Canada|Germany|Hungary|Israel|Italy|Mexico|Netherlands|Poland|Russian Federation|Spain|Switzerland|Turkey|United Kingdom 1
Korea, Republic of|Taiwan 1
Latvia 1
Lebanon 1
Mexico 1
Netherlands|United Kingdom 1
New Zealand 1
Poland 1
Romania 1
Singapore 1
Spain|United States|Australia|Brazil|Canada|Czechia|France|Germany|Israel|Italy|Netherlands|New Zealand|Poland|United Kingdom 1
Switzerland|United Kingdom 1
Taiwan|Australia|Germany|Hong Kong|Hungary|Japan|Korea, Republic of|Singapore 1
Thailand 1
Ukraine 1
United Kingdom|United States|Czechia|France|Hungary|Israel|Italy|Latvia|Poland|Spain 1
United States|Argentina|Australia|Austria|Brazil|Bulgaria|China|Denmark|France|Germany|Hong Kong|Hungary|Italy|Korea, Republic of|Poland|Portugal|Russian Federation|Singapore|Spain|Taiwan|Turkey 1
United States|Argentina|Australia|Brazil|Canada|Czechia|France|Germany|Israel|Italy|New Zealand|Poland|Puerto Rico|Spain|United Kingdom 1
United States|Argentina|Austria|Chile|Colombia|Czechia|France|Germany|Hong Kong|Israel|Korea, Republic of|Latvia|New Zealand|Philippines|Singapore|Spain|Switzerland 1
United States|Australia|Austria|Belgium|Czechia|France|Germany|Israel|Korea, Republic of|Malaysia|Netherlands|Portugal|Spain|Sweden|Switzerland|Taiwan 1
United States|Australia|Austria|France|Germany|Israel|Italy|Switzerland 1
United States|Australia|Belgium|Canada|Denmark|Germany|Italy|Japan|Sweden 1
United States|Australia|Belgium|Italy 1
United States|Australia|Brazil|Canada|Denmark|Hungary|Italy|Japan|Netherlands|Peru|Poland|Russian Federation|South Africa|Taiwan|Turkey|United Kingdom 1
United States|Australia|Czech Republic|France|Germany|Hungary 1
United States|Australia|France|Israel|Italy|Korea, Republic of|New Zealand|Portugal|United Kingdom 1
United States|Australia|Germany|Italy|Korea, Republic of|Philippines|Portugal 1
United States|Australia|Italy 1
United States|Australia|New Zealand 1
United States|Australia|Philippines 1
United States|Austria|Denmark|Hong Kong|India|Israel|Korea, Republic of|Philippines|Spain|Taiwan|Turkey 1
United States|Belgium|France|Germany|Italy|United Kingdom 1
United States|Brazil|Canada|Denmark|France|Germany|Italy|Netherlands|South Africa|Spain|United Kingdom 1
United States|Bulgaria|Czechia|Estonia|Hungary|India|Israel|Latvia|Lithuania|Poland|Romania|Russian Federation|Slovakia|Spain|Ukraine 1
United States|Colombia 1
United States|Croatia|Czechia|Estonia|Hungary|Israel|Latvia 1
United States|Croatia|Czechia|Estonia|Hungary|Japan|Korea, Republic of|Latvia|Poland|Russian Federation 1
United States|Czechia|Germany|Hungary|India|Korea, Republic of|Poland|Russian Federation|United Kingdom 1
United States|Czechia|Hungary|Latvia|United Kingdom 1
United States|Estonia|Hungary|Latvia 1
United States|France 1
United States|France|Germany|Hungary|Israel|Italy|Spain|United Kingdom 1
United States|Germany|Netherlands|United Kingdom 1
United States|Hungary|Latvia 1
United States|Mexico|Russian Federation 1
United States|Philippines 1
United States|Spain 1
United States|United Arab Emirates 1

Sites per Study

Site_count Study_Count
1 311
2 35
3 21
4 14
5 17
6 7
7 9
8 14
9 6
10 4
11 5
12 8
13 4
14 6
15 2
16 1
17 2
18 4
19 1
20 3
21 2
22 2
23 4
24 3
25 1
26 1
27 2
28 3
29 1
30 1
31 1
33 2
34 1
36 1
37 1
38 1
39 3
41 2
42 2
43 1
44 2
48 1
49 1
50 1
52 1
56 1
59 1
62 3
65 1
68 1
71 1
75 1
76 1
77 1
78 2
79 3
82 1
87 1
91 2
92 1
99 1
101 1
102 1
108 1
110 1
124 1
139 1
140 1
151 1
167 1
187 1
188 1
189 1

Phase

Phase Study_Count
N/A 128
Phase 2 119
Phase 1 81
Phase 3 80
Phase 4 67
Phase 1/Phase 2 56
Phase 2/Phase 3 15
Early Phase 1 3

Number of Arms

Number_of_Arms Count_of_Studies
1 157
2 188
3 68
4 40
5 11
6 12
7 3
8 2
10 1
12 1
NA 66

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 6.00000 3.0000 2.00000 4.00000 5.00000 15.0 10.0000 10.000
1st Qu. 13.00000 28.0000 17.50000 12.50000 29.50000 37.5 100.0000 37.000
Median 20.00000 60.0000 26.00000 26.00000 60.00000 55.0 329.5000 60.000
Mean 15.33333 998.1129 34.13924 40.69091 97.50862 134.4 755.6711 454.791
3rd Qu. 20.00000 134.2500 40.00000 40.50000 135.25000 112.5 655.2500 168.000
Max. 20.00000 60000.0000 180.00000 376.00000 510.00000 540.0 13475.0000 21445.000

Trial Group Type

group_type Group_Count
Experimental 675
Active Comparator 245
NA 66
Placebo Comparator 53
Other 50
Sham Comparator 31
No Intervention 29

Intervention Model

intervention_model Study_Count
Parallel Assignment 293
Single Group Assignment 194
NA 27
Sequential Assignment 14
Factorial Assignment 13
Crossover Assignment 8

Primary Purpose

primary_purpose Study_Count
Treatment 437
Prevention 30
Other 25
Basic Science 18
Diagnostic 13
Supportive Care 8
NA 8
Health Services Research 6
Screening 4

Observational Studies

Studies by Country

Country Study_Count
United States 78
NA 15
France 12
Israel 11
Germany 9
Switzerland 8
United Kingdom 8
Canada 7
Portugal 7
Austria 5
Japan 5
China 4
Korea, Republic of 3
Greece 2
Italy 2
Taiwan 2
Turkey 2
Argentina|Australia|Austria|Belgium|Brazil|Canada|Chile|China|Colombia|Costa Rica|Czech Republic|Dominican Republic|Ecuador|Egypt|France|Germany|Greece|Guatemala|Hong Kong|Hungary|India|Ireland|Israel|Italy|Japan|Korea, Republic of|Malaysia|Mexico|Netherlands|Panama|Peru|Poland|Portugal|Russian Federation|Saudi Arabia|Singapore|Slovakia|Slovenia|Spain|Turkey|Ukraine|United Kingdom|Venezuela 1
Argentina|Australia|Belgium|Canada|China|Colombia|Denmark|France|Greece|Ireland|Italy|Korea, Republic of|Norway|Spain|Sweden|Switzerland|Thailand|United Kingdom 1
Argentina|Colombia|Costa Rica|Mexico 1
Australia|Canada|France|Germany|Ireland|Italy|Japan|Netherlands|United Kingdom|Venezuela 1
Austria|Switzerland|United Kingdom 1
Belgium 1
Belgium|Cyprus|Czech Republic|Denmark|France|Germany|Greece|Ireland|Italy|Poland|Slovakia|Spain|Sweden 1
Czechia 1
Denmark 1
Denmark|France|Germany|Italy|Netherlands|Portugal|United Kingdom 1
France|Germany|Greece|Portugal|Russian Federation|Slovakia|Spain|United Kingdom 1
France|Germany|Italy|Spain|United Kingdom 1
India 1
Slovakia 1
Spain 1
Sweden 1
United States|Australia 1
United States|Australia|France|Germany|Netherlands|Poland|Spain|United Kingdom 1
United States|Austria 1
United States|France|Germany|United Kingdom 1
United States|Germany 1
United States|Germany|United Kingdom 1

Sites per Study

Site_count Study_Count
1 158
2 10
3 6
4 7
5 5
7 1
8 3
9 1
10 2
11 2
12 1
14 1
18 1
20 1
59 1
68 1
463 1

Enrollment Metrics

Measure Observational
Min 2.000
1st Qu 40.000
Median 104.000
Mean 783.495
3rd Qu 300.000
Max 30490.000

Observation Model

observational_model Study_Count
Cohort 110
Case-Only 22
Case-Control 19
Other 18
NA 17
Case Control 9
Case-Crossover 4
Ecologic or Community 3

Time Perspective

time_perspective Study_Count
Prospective 145
Retrospective 25
Cross-Sectional 19
NA 7
Other 6

Registries

Studies by Country

Country Study_Count
United States 2
France 1
NA 1

Sites per Study

Site_count Study_Count
1 3
3 1

Enrollment Metrics

Measure Registries
Min 200.0
1st Qu 282.5
Median 655.0
Mean 5377.5
3rd Qu 5750.0
Max 20000.0

Registry Model

observational_model Study_Count
Case-Control 2
Cohort 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 3
Cross-Sectional 1

Follow-up

target_duration Study_Count
1 Year 1
2 Years 1
20 Years 1
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03939767 Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease https://ClinicalTrials.gov/show/NCT03939767 Recruiting Bayer 2023-05-15
NCT03714308 Aflibercept Injection Into the Vitreous Body of the Eye: Study to Learn More About Patient Relevant Outcomes, Real World Treatment Patterns and How Well the Treatment Works for Patients Suffering From Abnormal Growth of New Blood Vessels Under the Retina. https://ClinicalTrials.gov/show/NCT03714308 Recruiting Bayer 2022-12-31
NCT03688243 Non Exudative AMD Imaged With SS-OCT https://ClinicalTrials.gov/show/NCT03688243 Recruiting Boston Image Reading Center 2022-01-31
NCT03470103 A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin America https://ClinicalTrials.gov/show/NCT03470103 Active, not recruiting Bayer 2020-09-30
NCT03382587 Observational Study to Assess Intravitreal Aflibercept Injections Used in a “Treat and Extend” Regimen in Treatment-naïve Wet Age-related Macular Degeneration Patients https://ClinicalTrials.gov/show/NCT03382587 Completed Bayer 2018-11-09
NCT03374020 Retinal Imaging Using NOTAL-OCT https://ClinicalTrials.gov/show/NCT03374020 Active, not recruiting Notal Vision Ltd 2019-12-30
NCT03372746 Generation of Induced Pluripotent Stem (iPS) Cell Lines From Skin Fibroblast Cells of Participants With Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT03372746 Completed National Institutes of Health Clinical Center (CC) 2019-03-21
NCT03823092 Polarization Perception in Health and Disease. Testing a New Sight Test https://ClinicalTrials.gov/show/NCT03823092 Recruiting South Warwickshire NHS Foundation Trust 2019-04-30
NCT03326401 The Potential Role of Dietary Antioxidant Capacity on Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT03326401 Completed Hacettepe University 2015-10-01
NCT03324542 Real World Outcomes of Intravitreal Anti-vascular Endothelial Growth Factors for Neovascular Age Related Macular Degeneration in Taiwan https://ClinicalTrials.gov/show/NCT03324542 Completed Changhua Christian Hospital 2017-10-13
NCT03322930 Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP) https://ClinicalTrials.gov/show/NCT03322930 Completed Retina Foundation of the Southwest 2019-03-01
NCT03318549 Evaluation of Visual and Task Performance https://ClinicalTrials.gov/show/NCT03318549 Enrolling by invitation Duke University 2022-12-31
NCT03313401 Effect of Aflibercept on Human Corneal Endothelial Cells in Neovascular Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT03313401 Completed Ulucanlar Eye Training and Research Hospital 2017-05-31
NCT03278262 The Impact of Baseline Visual Acuity on the Treatment Outcomes in Patients Treated With AflIbercept in Real-life Clinical Setting https://ClinicalTrials.gov/show/NCT03278262 Completed Bayer 2017-12-31
NCT03275753 Visual Function Tests in Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT03275753 Recruiting ORA, Inc. 2019-12-31
NCT03242083 Evaluate the Quality of Life of Patients With AMD https://ClinicalTrials.gov/show/NCT03242083 Completed Centre Hospitalier Universitaire Dijon 2019-12-03
NCT03225131 Dark Adaptation in Participants With Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT03225131 Recruiting National Institutes of Health Clinical Center (CC) 2029-12-31
NCT03222362 Pars Plana Vitrecromy in Patients Aged 85 Years and Above https://ClinicalTrials.gov/show/NCT03222362 Completed Tel Aviv Medical Center 2013-12-31
NCT03166202 Age-Related Macular Degeneration, Scotopic Dysfunction, and Driving Performance in a Simulator https://ClinicalTrials.gov/show/NCT03166202 Completed University of Alabama at Birmingham 2019-03-05
NCT03102138 Retinal Pigment Epithelium Safety Study For Patients In B4711001 https://ClinicalTrials.gov/show/NCT03102138 Active, not recruiting Moorfields Eye Hospital NHS Foundation Trust 2020-10-04
NCT03092492 AMD Ryan Initiative Study (ARIS) https://ClinicalTrials.gov/show/NCT03092492 Recruiting National Institutes of Health Clinical Center (CC) 2023-10-25
NCT03079570 Flicker Fusion Thresholds Between Young and Old Subjects at Various Luminance Levels https://ClinicalTrials.gov/show/NCT03079570 Completed ORA, Inc. 2016-09-08
NCT03076697 Smartphone Screening for Eye Diseases https://ClinicalTrials.gov/show/NCT03076697 Enrolling by invitation University of Michigan 2023-06-30
NCT03035461 Patient’s Feelings After Receiving a Diagnosis of Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT03035461 Completed Centre Hospitalier Intercommunal Creteil 2018-02-01
NCT03030729 Macular Thickness Measurements Using Retinal-thickness OCT https://ClinicalTrials.gov/show/NCT03030729 Completed Notal Vision Ltd 2018-01-14
NCT02941991 A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt’s Macular Dystrophy (SMD) https://ClinicalTrials.gov/show/NCT02941991 Completed Astellas Pharma Inc 2019-10-02
NCT02941263 Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT02941263 Recruiting National Institutes of Health Clinical Center (CC) 2022-12-31
NCT02875704 Oxidative Stress In Stargardt Disease, Age Related Macular Degeneration and Diabetic Retinopathy https://ClinicalTrials.gov/show/NCT02875704 Recruiting Johns Hopkins University 2021-05-31
NCT02748824 Five-year Incidence of Age-related Macular Degeneration in the Central Region of Portugal https://ClinicalTrials.gov/show/NCT02748824 Completed Association for Innovation and Biomedical Research on Light and Image 2017-09-18
NCT02669953 Aflibercept in Recurrent or Persistent CNV https://ClinicalTrials.gov/show/NCT02669953 Recruiting Medical University of Vienna 2020-12-31
NCT02615496 Evaluation of Physician and Patient Knowledge of Safety and Safe Use Information for Aflibercept https://ClinicalTrials.gov/show/NCT02615496 Completed Bayer 2016-09-30
NCT02588378 The Role of Inflammation in AMD and Related Disorders https://ClinicalTrials.gov/show/NCT02588378 Recruiting St. Michael’s Hospital, Toronto 2020-05-31
NCT02585401 Evaluation of Physician Knowledge of Safety and Safe Use Information for Aflibercept in Canada https://ClinicalTrials.gov/show/NCT02585401 Completed Bayer 2016-03-31
NCT02422160 Vision Outcomes Using Quantitative Optical Coherence Tomography Evaluation in Age Related Macular Degeneration https://ClinicalTrials.gov/show/NCT02422160 Recruiting Stanford University 2021-12-31
NCT02567604 Development of Core Outcomes for Age-related Macular Degeneration (AMD) Interventions- Caregivers’ Perspective https://ClinicalTrials.gov/show/NCT02567604 Completed Queen’s University, Belfast 2018-09-30
NCT01496625 National Eye Institute Biorepository for Retinal Diseases https://ClinicalTrials.gov/show/NCT01496625 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT02550002 Comparison of Treatment rOutine Using afLibERcept: Strict vs relAxed retreatmeNT Regimen https://ClinicalTrials.gov/show/NCT02550002 Active, not recruiting University Hospital Inselspital, Berne 2022-03-31
NCT02541084 Caregiver Burden of Wet Age-related Macular Degeneration (wAMD) in Japan https://ClinicalTrials.gov/show/NCT02541084 Completed Bayer 2016-03-30
NCT02540369 To Describe the Use of Intravitreal Aflibercept and to Describe Follow-up as Well as Treatment Patterns in Patients With Wet Age-related Macular Degeneration (wAMD) or Diabetic Macular Edema (DME) in Routine Clinical Practice in Canada. https://ClinicalTrials.gov/show/NCT02540369 Completed Bayer 2017-09-25
NCT02528058 Ultrastructure Analysis of Excised Internal Limiting Membrane in Eyes of Highly Myopia With Myopic Traction Maculopathy https://ClinicalTrials.gov/show/NCT02528058 Completed Kyorin University 2014-07-31
NCT02528045 Vitrectomy and Scleral Shortening for Macular Hole Retinal Detachment or Myopic Traction Maculopathy https://ClinicalTrials.gov/show/NCT02528045 Completed Kyorin University 2014-07-31
NCT02028351 Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions https://ClinicalTrials.gov/show/NCT02028351 Completed Sinclair Technologies, LLC 2009-03-31
NCT02452840 Photodynamic Therapy for PDA in NV AMD https://ClinicalTrials.gov/show/NCT02452840 Recruiting Duke University 2022-05-31
NCT02445612 Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Stargardt Macular Dystrophy Patients https://ClinicalTrials.gov/show/NCT02445612 Completed Astellas Pharma Inc 2019-06-21
NCT02445313 Measuring Geographic Atrophy in AMD Patients Using the Nidek MP-3 Microperimetry Device https://ClinicalTrials.gov/show/NCT02445313 Completed Doheny Image Reading Center 2019-02-12
NCT02438111 The Role of the Gut Metagenome on the Development of Age Related Macular Degeneration (AMD) https://ClinicalTrials.gov/show/NCT02438111 Recruiting University Hospital Inselspital, Berne 2020-11-30
NCT02420132 Study to Evaluate Home Vision Testing in Participants Who Receive Ranibizumab (Lucentis®) https://ClinicalTrials.gov/show/NCT02420132 Completed Hoffmann-La Roche 2016-08-25
NCT02410122 The Natural History of the Progression of Atrophy Secondary to Stargardt Disease Type 4: PROM1-Related Macular Dystrophy https://ClinicalTrials.gov/show/NCT02410122 Completed Johns Hopkins University 2018-03-31
NCT02367365 Neovascular Morphology and Persistent Disease Activity Among Patients With NV AMD https://ClinicalTrials.gov/show/NCT02367365 Completed Duke University 2017-12-31
NCT02332343 Sparing of the Fovea in Geographic Atrophy Progression https://ClinicalTrials.gov/show/NCT02332343 Completed University Hospital, Bonn 2017-01-31
NCT02321241 Real Life of Aflibercept in France in Patients Refractory to Ranibizumab: Observational Study in Wet AMD https://ClinicalTrials.gov/show/NCT02321241 Completed Bayer 2017-01-18
NCT02313259 The Impact of Ocular Diseases on Driving: a Prospective Study https://ClinicalTrials.gov/show/NCT02313259 Completed CHU de Quebec-Universite Laval 2015-02-23
NCT02308215 Retinal Therapy Guided by 3D OCT Image Analysis https://ClinicalTrials.gov/show/NCT02308215 Completed University of Iowa 2018-07-05
NCT02291887 Genetic Analysis of Patients Responsive to Ranibizumab But Resistant to Aflibercept https://ClinicalTrials.gov/show/NCT02291887 Completed Associated Retinal Consultants, Michigan 2015-07-01
NCT02289924 Aflibercept (Eylea) in roUtine Clinical Practice in patientS With Wet Age-related Macular Degeneration in Italy https://ClinicalTrials.gov/show/NCT02289924 Completed Bayer 2019-03-28
NCT02287298 Triple Combination Therapy of Choroidal Neovascularization in AMD, a Cost Effect and Efficient Therapeutic Treatment https://ClinicalTrials.gov/show/NCT02287298 Completed The Retina Center of St. Louis County, PC 2015-12-31
NCT02279537 Real Life of Aflibercept In FraNce: oBservatiOnnal Study in Wet AMD https://ClinicalTrials.gov/show/NCT02279537 Completed Bayer 2019-04-17
NCT02253030 OCT Angiography in Wet AMD https://ClinicalTrials.gov/show/NCT02253030 Recruiting Oregon Health and Science University 2022-12-31
NCT02225119 The Focal Electro-Oculogram in Macular Disease https://ClinicalTrials.gov/show/NCT02225119 Completed National Institutes of Health Clinical Center (CC) 2019-05-07
NCT02218177 Intraocular Cytokines in Non-responders to Ranibizumab Treatment for Neovascular AMD https://ClinicalTrials.gov/show/NCT02218177 Completed University Health Network, Toronto 2016-08-31
NCT02173496 Colour Contrast Sensitivity for the Early Detection of Wet Age-related Macular Degereration (CEDAR) https://ClinicalTrials.gov/show/NCT02173496 Completed Aston University 2017-05-31
NCT02162953 Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases. https://ClinicalTrials.gov/show/NCT02162953 Active, not recruiting Mayo Clinic 2021-12-31
NCT02126423 Resistance to Antibiotics in Patients Receiving Eye Injections https://ClinicalTrials.gov/show/NCT02126423 Completed Prism Vision Group 2014-09-30
NCT01318941 Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting https://ClinicalTrials.gov/show/NCT01318941 Completed Novartis 2016-04-30
NCT02090751 Development of a Device to Measure Dark Adaptation https://ClinicalTrials.gov/show/NCT02090751 Completed University of Manchester 2015-02-28
NCT01310686 Genetics Study of Wet Age-Related Macular Degeneration (AMD) Non-Responders to Vascular Endothelial Growth Factor (VEGF) Therapy https://ClinicalTrials.gov/show/NCT01310686 Active, not recruiting West Coast Retina Medical Group, Inc. 2019-06-30
NCT01298674 Epidemiological Study of the Prevalence of Age-Related Macular Degeneration in Portugal https://ClinicalTrials.gov/show/NCT01298674 Completed Association for Innovation and Biomedical Research on Light and Image 2013-10-31
NCT01272076 Cirrus HD-OCT Measurement of Area of Increased Light Penetration Under the Retinal Pigment Epithelium (RPE) https://ClinicalTrials.gov/show/NCT01272076 Completed Carl Zeiss Meditec, Inc. 2011-02-28
NCT01272063 Measurement and Analysis of Macular Retinal Pigment Epithelium (RPE) Elevations With Cirrus HD-OCT vs. Color Fundus Photography https://ClinicalTrials.gov/show/NCT01272063 Completed Carl Zeiss Meditec, Inc. 2011-02-28
NCT02055612 Mobile Clinic - a Cross-sectional Epidemiological Survey https://ClinicalTrials.gov/show/NCT02055612 Completed Novartis 2013-05-31
NCT02051998 Directional Spread in Geographic Atrophy https://ClinicalTrials.gov/show/NCT02051998 Completed University Hospital, Bonn 2019-11-30
NCT01996215 Brain Connectivity in Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT01996215 Completed Duke University 2018-06-30
NCT01977846 A Natural History of the Progression of Stargardt Disease: Retrospective and Prospective Studies https://ClinicalTrials.gov/show/NCT01977846 Completed Foundation Fighting Blindness 2017-02-28
NCT01942213 Observational Study to Evaluate and Compare the Rate and Extent of Inflammation After a Single Intravitreal Injection of Ranibizumab vs. a Single Intravitreal Injection of Aflibercept in Treatment Naive and Treatment Experienced Patients. https://ClinicalTrials.gov/show/NCT01942213 Completed Prism Vision Group 2016-04-30
NCT01915238 Study of the Effects of Supplements on Eye Disease in Participants From the Age-Related Eye Disease Study https://ClinicalTrials.gov/show/NCT01915238 Completed National Institutes of Health Clinical Center (CC) 2014-06-20
NCT01914380 Investigating the Effectiveness of Eylea in Patients With Wet Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT01914380 Completed Bayer 2017-03-31
NCT01880788 Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMD https://ClinicalTrials.gov/show/NCT01880788 Completed Sequenom, Inc. 2015-03-31
NCT01876147 Visual and Functional Assessment in Low Vision Patients https://ClinicalTrials.gov/show/NCT01876147 Completed University of Oxford 2016-03-31
NCT01846351 Intravitreal Anti-VEGF in Exudative AMD With Epiretinal Membranes https://ClinicalTrials.gov/show/NCT01846351 Completed New England Retina Associates 2010-02-28
NCT01822873 Study on Visual Function Impairments in Dry Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT01822873 Completed Duke University 2018-07-31
NCT01783925 Eylea Post Marketing Surveillance(PMS) https://ClinicalTrials.gov/show/NCT01783925 Completed Bayer 2018-12-31
NCT01778491 AMD Phenotype and Genotype Study https://ClinicalTrials.gov/show/NCT01778491 Completed National Institutes of Health Clinical Center (CC) 2015-09-29
NCT01771081 Evaluation of Changes in Visual Acuity in Patients With Diabetic Macular Edema (DME) Starting Treatment With an Approved Anti-VEGF Therapy https://ClinicalTrials.gov/show/NCT01771081 Completed Bayer 2015-01-31
NCT01756261 EYLEA [AMD-QOL(Age-Related Macular Degeneration-Quality of Life)] Post-marketing Surveillance in Japan https://ClinicalTrials.gov/show/NCT01756261 Completed Bayer 2016-07-20
NCT01756248 EYLEA Age-Related Macular Degeneration (AMD) Post-marketing Surveillance in Japan https://ClinicalTrials.gov/show/NCT01756248 Completed Bayer 2018-12-31
NCT01715870 Life Style and Food Habits Questionnaire in the Portuguese Population Aged 55 or More https://ClinicalTrials.gov/show/NCT01715870 Completed Association for Innovation and Biomedical Research on Light and Image 2014-04-30
NCT01712841 Non-exudative Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT01712841 Completed Oregon Health and Science University 2018-01-18
NCT01712035 Neovascular Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT01712035 Completed Oregon Health and Science University 2017-12-05
NCT01692938 Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO https://ClinicalTrials.gov/show/NCT01692938 Completed Optos, PLC 2012-11-30
NCT01682382 Association of Macular Pigment Optical Density (MPOD) and Genetic Variants in Complement Factor H in Subjects With Choroidal Neovascular (CNV) https://ClinicalTrials.gov/show/NCT01682382 Completed Sequenom, Inc. 2013-08-31
NCT01670643 Reading Performance With a Video Magnifier https://ClinicalTrials.gov/show/NCT01670643 Completed Massachusetts Eye and Ear Infirmary 2010-04-30
NCT03349801 Development of Novel Clinical Endpoints in Intermediate AMD https://ClinicalTrials.gov/show/NCT03349801 Recruiting University Hospital, Bonn 2022-02-28
NCT01666821 A Population-based Study of Macular Choroidal Neovascularization in a Chinese Population https://ClinicalTrials.gov/show/NCT01666821 Completed Shanghai University of Traditional Chinese Medicine 2008-09-30
NCT01650948 Genetic Load and Phenotype in Aggressive AMD https://ClinicalTrials.gov/show/NCT01650948 Completed Sequenom, Inc. 2013-12-31
NCT01644513 Evaluation of the Association Between Genetic Load and Response to Anti-VEGF Therapy in AMD Patients https://ClinicalTrials.gov/show/NCT01644513 Completed Sequenom, Inc. 2012-12-31
NCT01581606 Evaluation of TeleOphthalmology in AMD-TeleMedicine Solutions to Improve Patient Access and Quality of Vision Outcomes https://ClinicalTrials.gov/show/NCT01581606 Completed Lawson Health Research Institute 2014-04-04
NCT01553474 Blood and Saliva Sample Collection for AREDS 2 https://ClinicalTrials.gov/show/NCT01553474 Completed National Institutes of Health Clinical Center (CC) NA
NCT01527435 Addition of 20mg/Day Zeaxanthin to Triple Therapy Treatment Options for Age Related Macular Degeneration (ARMD) https://ClinicalTrials.gov/show/NCT01527435 Completed The Retina Center of St. Louis County, PC 2015-12-31
NCT01526070 Study of Bimonthly VEGF Trap-Eye Compared to As-needed Administration or Other Therapy for Exudative Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT01526070 Completed Stanford University 2014-07-31
NCT01464710 Genetic Assessment of Early to Late Macular Degeneration Study https://ClinicalTrials.gov/show/NCT01464710 Completed University of California, San Diego 2015-01-31
NCT01448538 Non-Persistence/Non-Adherence (NP/NA) in Wet Age-related Macular Degeneration (wAMD) Patients in Germany https://ClinicalTrials.gov/show/NCT01448538 Completed Bayer 2013-12-31
NCT01447043 Study to Assess the Effectiveness of Existing Anti vascUlar Endothelial Growth Factor (Anti VEGF) in Patients With Wet Age-related Macular Degeneration (wAMD) (AURA) https://ClinicalTrials.gov/show/NCT01447043 Completed Bayer 2011-08-31
NCT01334294 Home Vision Monitoring Using the ForeseeHome Device Following Treatment of Neovascular Age Related Macular Degeneration https://ClinicalTrials.gov/show/NCT01334294 Completed Notal Vision Ltd 2013-12-31
NCT01330797 The Effect of Ranibizumab on Eye Lens Opacity in Cases With Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT01330797 Completed Uludag University 2010-10-31
NCT00594672 Age-Related Eye Disease Study (AREDS) Follow-Up https://ClinicalTrials.gov/show/NCT00594672 Active, not recruiting National Institutes of Health Clinical Center (CC) NA
NCT04395859 Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents https://ClinicalTrials.gov/show/NCT04395859 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2021-12-31
NCT04377295 Evaluation of Retinal and Vascular Features in Radiation Maculopathy After Intravitreal Injections of Ranibizumab https://ClinicalTrials.gov/show/NCT04377295 Completed Federico II University 2019-10-01
NCT04349254 Observational Study of Vision Improvement in Late Stage Dry AMD Patients https://ClinicalTrials.gov/show/NCT04349254 Recruiting Optimal Acuity Corporation 2020-12-31
NCT04281732 Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision https://ClinicalTrials.gov/show/NCT04281732 Recruiting Queen’s University, Belfast 2020-09-30
NCT04278300 Study of the Discriminating Power of a Blood Biomarker for Omega-3 Polyunsaturated Fatty Acid Content of the Retina for Age-related Macular Degeneration (AMD) https://ClinicalTrials.gov/show/NCT04278300 Recruiting Centre Hospitalier Universitaire Dijon 2022-02-28
NCT04270604 Biological Sample Collection for Research and Biobanking https://ClinicalTrials.gov/show/NCT04270604 Recruiting The New York Stem Cell Foundation 2030-01-31
NCT04269304 Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - PINNACLE https://ClinicalTrials.gov/show/NCT04269304 Recruiting University of Southampton 2023-12-31
NCT04196049 Removal of Massive Subretinal Organized Blood Clot With Fragmatome https://ClinicalTrials.gov/show/NCT04196049 Completed Changhua Christian Hospital 2019-10-31
NCT04187157 Association Between Light Spectrum and Survival After Cataract Surgery https://ClinicalTrials.gov/show/NCT04187157 Completed University of Pittsburgh 2019-04-30
NCT04169802 Study Evaluating Retinal Health Monitoring System Visual Acuity Module. https://ClinicalTrials.gov/show/NCT04169802 Completed Kubota Vision Inc. 2020-04-15
NCT04138420 Evaluation of Retinal and Vascular Features in Macular Degeneration After Intravitreal Injections of Bevacizumab https://ClinicalTrials.gov/show/NCT04138420 Completed Federico II University 2017-10-25
NCT04112667 Functionally Validated Structural Endpoints for Early AMD https://ClinicalTrials.gov/show/NCT04112667 Recruiting University of Alabama at Birmingham 2024-02-29
NCT04101604 Biomarkers of Common Eye Diseases https://ClinicalTrials.gov/show/NCT04101604 Recruiting Sun Yat-sen University 2020-10-01
NCT04067583 A Follow-up Physician Survey to Evaluate Physician Knowledge of Safety and Safe Use Information for Aflibercept Administered by Intravitreal Injection in Europe https://ClinicalTrials.gov/show/NCT04067583 Recruiting Bayer 2020-06-30
NCT04032808 Evaluation of the Performance of Self-monitoring Optimized by Therapeutic Education in the Recurrence of Wet Age-related Macular Degeneration (AMD) https://ClinicalTrials.gov/show/NCT04032808 Recruiting Clinique Beau Soleil 2021-07-10
NCT03999801 Long-term Follow-Up Study of RGX-314 https://ClinicalTrials.gov/show/NCT03999801 Enrolling by invitation Regenxbio Inc. 2024-06-30
NCT03969303 NOTAL-OCT V.2.5 vs Commercial OCT in AMD Patients https://ClinicalTrials.gov/show/NCT03969303 Recruiting Notal Vision Ltd 2019-10-20
NCT03939195 OCTA (Optical Coherence Angiography Tomography) Versus Structural OCT(Optical Coherence Tomography) in Neovascular AMD (Age Macular Degeneration) https://ClinicalTrials.gov/show/NCT03939195 Recruiting Centre Hospitalier Intercommunal Creteil 2019-07-31
NCT03927430 Surgical Outcome of Macular Membrane Peeling Associated With Significant Macular Drusen https://ClinicalTrials.gov/show/NCT03927430 Completed Klinikum Chemnitz gGmbH 2019-03-01
NCT03838679 Imaging of the Angiofibrotic Switch in Neovascular AMD https://ClinicalTrials.gov/show/NCT03838679 Recruiting Medical University of Vienna 2022-04-28
NCT03803631 CNV in AMD Analyzed by OCT Angiography Under IntravitreaL Eylea (COCTAEyl) https://ClinicalTrials.gov/show/NCT03803631 Recruiting Centre Hospitalier Intercommunal Creteil 2021-05-30
NCT03744806 Blood-aqueous Barrier Integrity in Eyes Undergoing Intravitreal Bevacizumab Therapy to Treat Neovascular AMD https://ClinicalTrials.gov/show/NCT03744806 Completed Medical University of Lublin 2015-09-30
NCT03680326 Intravitreal Anti-vascular Endothelial Growth Factor Administration and Its Influence on Vitreomacular Interface- and Retinal Morphology in Eyes With Neovascular Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT03680326 Completed Hospital Hietzing 2018-03-22
NCT03679156 Retinal Pigment Epithelial Characteristics in Eyes With Neovascular Age-related Macular Degeneration Following Long-term Treatment With Anti Neovascular Endothelial Growth Factor https://ClinicalTrials.gov/show/NCT03679156 Completed Hospital Hietzing 2016-11-02
NCT03614481 Clinical and Genetic Analyzes of Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT03614481 Recruiting Centre Hospitalier Intercommunal Creteil 2022-11-30
NCT03521895 An Integrated Analysis of the Effectiveness of Intravitreal (IVT) Aflibercept (Eylea) in Routine Clinical Practice Based on Two Large Observational Studies https://ClinicalTrials.gov/show/NCT03521895 Completed Bayer 2018-11-30
NCT03504540 Comparison of Complement Factors and Genetic Polymorphisms of AMD Between Patients With Systemic Lupus Erythematosus (SLE) With and Without Retinal “Pseudo-drusen-like” Deposits: Case-control Study (PL-AMD) https://ClinicalTrials.gov/show/NCT03504540 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2021-04-30
NCT03476291 Research of Automated Maculopathy Screening Based on AI Techniques Using OCT Images https://ClinicalTrials.gov/show/NCT03476291 Active, not recruiting The First Affiliated Hospital with Nanjing Medical University 2018-06-01
NCT03438669 Correlation Between Visual Acuity Measurements, Quality of Life and Morphological Parameters in Wet AMD Patients https://ClinicalTrials.gov/show/NCT03438669 Completed Vista Klinik 2017-05-30
NCT03433885 Wenzhou Dry Age-related Macular Degeneration (AMD) Progression Study https://ClinicalTrials.gov/show/NCT03433885 Recruiting The Eye Hospital of Wenzhou Medical University 2020-12-31
NCT03415984 Prevalence of Age Related Macular Degeneration (ARMD) in Parkinson’s Patients and Assesment of the Role of L-DOPA https://ClinicalTrials.gov/show/NCT03415984 Completed Fondation Ophtalmologique Adolphe de Rothschild 2019-01-15
NCT03411941 Evaluate the Effectiveness of Intravitreal (IVT) Aflibercept Injection in Clinical Practice in naïve Patients With Neovascular Age-related Macular Degeneration (nAMD) https://ClinicalTrials.gov/show/NCT03411941 Completed Bayer 2019-03-01
NCT01256827 Seven Year Update of Macular Degeneration Patients https://ClinicalTrials.gov/show/NCT01256827 Completed University of California, San Francisco 2012-10-31
NCT01245387 Observational Study Of The Long-Term Effect Of Macugen In Patients With Wet Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT01245387 Completed Pfizer 2009-12-31
NCT01233128 Vascular Endothelial Growth Factor (VEGF) & LOC387715/HTRA1 Polymorphism in Polypoidal Choroidal Vasculopathy https://ClinicalTrials.gov/show/NCT01233128 Completed Kyungpook National University Hospital 2012-01-31
NCT01233115 LOC387715/HTRA1 and the Combined Photodynamic Therapy With Intravitreal Bevacizumab in Polypoidal Choroidal Vasculopathy https://ClinicalTrials.gov/show/NCT01233115 Completed Kyungpook National University Hospital 2011-08-31
NCT01204541 A Single-Center Pilot Study to Assess Macular Function https://ClinicalTrials.gov/show/NCT01204541 Completed ORA, Inc. 2010-10-31
NCT01115387 GARM II: A Study on the Genetics of Age-related Maculopathy https://ClinicalTrials.gov/show/NCT01115387 Active, not recruiting University of California, Los Angeles 2016-02-29
NCT01115231 Complement Factor H Haplotypes and Smoking in Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT01115231 Completed VA Office of Research and Development 2015-06-30
NCT01083147 Age-Related Macular Degeneration (AMD) - Beta Study Telemedicine Assessment https://ClinicalTrials.gov/show/NCT01083147 Completed Notal Vision Ltd 2010-03-31
NCT01080898 Evaluation of Optical Coherence Tomography. https://ClinicalTrials.gov/show/NCT01080898 Completed Assistance Publique - Hôpitaux de Paris 2010-10-31
NCT01073592 Comparison Between Foresee Home and Optical Coherence Tomography (OCT) Visual Field Defects in Patients With Choroidal Neovascularization (CNV) https://ClinicalTrials.gov/show/NCT01073592 Completed Notal Vision Ltd 2013-01-31
NCT01010997 Foresee Home for Monitoring Age Related Macular Degeneration (AMD) https://ClinicalTrials.gov/show/NCT01010997 Completed Notal Vision Ltd 2012-01-31
NCT00963339 Age-Related Macular Degeneration (AMD) - Usability Study https://ClinicalTrials.gov/show/NCT00963339 Completed Notal Vision Ltd 2009-12-31
NCT00927303 The Spectralis-Cirrus Study https://ClinicalTrials.gov/show/NCT00927303 Completed The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery 2009-12-31
NCT00884637 Correlation Between Visual Field Defects on FORESEE HOME and on Optical Coherence Tomography in Choroidal Neovascularization Subjects https://ClinicalTrials.gov/show/NCT00884637 Completed Notal Vision Ltd 2013-12-31
NCT00873106 Retinal Thickness and Volume Estimates Given by Time Domain and Spectral Optical Coherence Tomography https://ClinicalTrials.gov/show/NCT00873106 Completed Glostrup University Hospital, Copenhagen 2010-03-31
NCT00858208 Efficacy And Safety Of Macugen In Patients With Neovascular AMD In Routine Clinical Practice. https://ClinicalTrials.gov/show/NCT00858208 Completed Pfizer 2011-04-30
NCT00845273 Long-Term Use Of Pegaptanib In Patients For Subfoveal Choroidal Neovascularization Secondary To Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT00845273 Completed Pfizer 2014-02-28
NCT00831961 Antibiotic Resistant Patterns of Conjunctival and Nasophayngeal Flora After Repeated Exposure to Topical Antibiotics https://ClinicalTrials.gov/show/NCT00831961 Completed Vanderbilt University 2009-11-30
NCT03833830 Vessel Density in nAMD After Longterm Anti-VEGF Treatment Compared to Recently Started Anti-VEGF Treatment https://ClinicalTrials.gov/show/NCT03833830 Completed Vista Klinik 2019-04-02
NCT01933152 Study to Assess the EffectiVeness of exIsting Anti-vascular Endothelial groWth Factor (Anti-VEGF) Treatment Regimens in Patients With Wet Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT01933152 Completed Bayer 2013-04-30
NCT03894020 To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD) https://ClinicalTrials.gov/show/NCT03894020 Recruiting Gyroscope Therapeutics 2023-01-08
NCT03290794 Structured Post-marketing Surveillance to Collect the Safety Data of Intravitreal Aflibercept Injection (IVT-AFL) in Patients of Wet Age-related Macular Degeneration During Real World Clinical Practice https://ClinicalTrials.gov/show/NCT03290794 Recruiting Bayer 2020-12-31
NCT00801541 Characterization of Early Markers of Choroidal Neovascularization https://ClinicalTrials.gov/show/NCT00801541 Completed Association for Innovation and Biomedical Research on Light and Image 2008-12-31
NCT02821247 Prospective Observational Study to Assess Effectiveness of Intravitreal Aflibercept in Patients With Wet Macular Degeneration in Greece https://ClinicalTrials.gov/show/NCT02821247 Completed Bayer 2019-07-10
NCT02521142 Non-invasive Optical Angiography in Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT02521142 Recruiting Medical University of Vienna 2020-12-31
NCT02463344 Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Patients With AMD https://ClinicalTrials.gov/show/NCT02463344 Completed Astellas Pharma Inc 2019-08-19
NCT01352975 Study of Dark Adaptation in Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT01352975 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT03760055 Assessment of Visual Function With a Portable Brain-computer Interface https://ClinicalTrials.gov/show/NCT03760055 Enrolling by invitation NGoggle 2024-01-31
NCT00791427 ERG/EOG Study in AMD Patients Treated With Ranibizumab https://ClinicalTrials.gov/show/NCT00791427 Completed Retina Center, Minnesota 2011-09-30
NCT00787319 Long-Term Non-Interventional Study (NIS) To Investigate The Safety And Effectiveness Of MACUGEN In Patients With Neovascular Age-Related Macular Degeneration Under Conditions Of Routine Clinical Practice https://ClinicalTrials.gov/show/NCT00787319 Completed Pfizer 2012-06-30
NCT00776451 Usability of the PreView PHP for Home Use in Intermediate AMD Patients https://ClinicalTrials.gov/show/NCT00776451 Completed Notal Vision Ltd 2009-02-28
NCT00759044 Validation of a New Methodology for Mapping the Human Blood-Retinal Barrier Function https://ClinicalTrials.gov/show/NCT00759044 Completed Association for Innovation and Biomedical Research on Light and Image 2010-10-31
NCT00748384 Usability of the Foresee Home in Intermediate Age Related Macular Degeneration (AMD) Patients https://ClinicalTrials.gov/show/NCT00748384 Completed Notal Vision Ltd 2013-03-31
NCT00734487 AREDS 2 Ancillary Spectral Domain Optical Coherence Tomography Study https://ClinicalTrials.gov/show/NCT00734487 Completed Duke University 2015-08-31
NCT00727753 VEGF-antagonism and Endothelial Function in Age-related Macular Degeneration (AMD) https://ClinicalTrials.gov/show/NCT00727753 Completed University of Zurich 2012-12-31
NCT00692887 Correlation Between Visual Field Defects on Foresee Preferential Hyperacuity Perimeter(PHP) and on Optical Coherence Tomography (OCT) in Patients With Choroidal Neovascularization (CNV) https://ClinicalTrials.gov/show/NCT00692887 Completed Notal Vision Ltd 2008-12-31
NCT00668213 Antioxidant Systems and Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT00668213 Completed Vanderbilt University 2010-06-30
NCT00656903 High Speed Indocyanine Green Angiography Findings in Ranibizumab Treatment for Wet Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT00656903 Completed National Institutes of Health Clinical Center (CC) NA
NCT00647439 Genetics and Markers of Degenerative and Inflammatory Eye Diseases https://ClinicalTrials.gov/show/NCT00647439 Completed National Institutes of Health Clinical Center (CC) NA
NCT00605943 Detection of Neutralizing Antibodies in Patients Treated With Bevacizumab or Ranibizumab https://ClinicalTrials.gov/show/NCT00605943 Completed National Institutes of Health Clinical Center (CC) 2009-08-04
NCT00604071 Sensitivity of the Home Macular Perimeter (HMP) https://ClinicalTrials.gov/show/NCT00604071 Completed Notal Vision Ltd 2008-09-30
NCT00603850 Testing the Effectiveness of the Interactive Tutorial of the Home Macular Perimeter (HMP) https://ClinicalTrials.gov/show/NCT00603850 Completed Notal Vision Ltd 2008-04-30
NCT00596388 Usage of the Home Macular Perimeter (HMP) https://ClinicalTrials.gov/show/NCT00596388 Completed Notal Vision Ltd 2013-01-31
NCT00595998 Sensitivity and Specificity of the Home Macular Perimeter (HMP) https://ClinicalTrials.gov/show/NCT00595998 Completed Notal Vision Ltd 2008-09-30
NCT00592826 HMP (Home Macular Perimeter) -Usability Trial https://ClinicalTrials.gov/show/NCT00592826 Completed Notal Vision Ltd 2008-01-31
NCT00559234 Potential Research Participants for Future Studies of Inherited Eye Diseases https://ClinicalTrials.gov/show/NCT00559234 Completed National Institutes of Health Clinical Center (CC) NA
NCT00556114 A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging https://ClinicalTrials.gov/show/NCT00556114 Completed University of California, Irvine 2013-07-31
NCT00549055 A Study On The Efficacy Of Macugen Injections In Patients With Neovascular Age-Related Macular Degeneration In Real Life. https://ClinicalTrials.gov/show/NCT00549055 Completed Pfizer 2009-10-31
NCT00531141 The Optical Coherence Tomography in Age-Related Macular Degeneration Study: The OCT in AMD Study https://ClinicalTrials.gov/show/NCT00531141 Completed The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery 2008-06-30
NCT00494325 The Role of Macular Pigment in Patients With Age-related Macular Degeneration https://ClinicalTrials.gov/show/NCT00494325 Completed University Hospital Inselspital, Berne 2010-12-31
NCT00465400 Oxidative Stress in Patients With Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT00465400 Completed University Hospital, Basel, Switzerland 2007-12-31
NCT00460408 Ocular Safety Of Patients Receiving Macugen For Neovascular Age Related Macular Degeneration https://ClinicalTrials.gov/show/NCT00460408 Completed Pfizer 2012-02-29
NCT00417846 Age-related Macular Degeneration: Detection of Onset of New Choroidal Neovascularization (AMD DOC Study) https://ClinicalTrials.gov/show/NCT00417846 Completed Johns Hopkins University 2009-08-31
NCT00393692 Fundus Autofluorescence Imaging in Age-related Macular Degeneration Using Confocal Scanning Laser Ophthalmoscopy https://ClinicalTrials.gov/show/NCT00393692 Completed University Hospital, Bonn 2016-04-30
NCT00359008 PHP Home Preferential Hyperacuity Perimeter for the Detection of Choroidal Neovascularization (CNV) https://ClinicalTrials.gov/show/NCT00359008 Completed Notal Vision Ltd NA
NCT00358345 PreView PHP Preferential Hyperacuity Perimeter for the Detection of Choroidal Neovascularization https://ClinicalTrials.gov/show/NCT00358345 Completed Notal Vision Ltd NA
NCT00357578 Genetic Study of Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT00357578 Completed National Institutes of Health Clinical Center (CC) NA
NCT00343603 Tracking Optical Coherence Tomography https://ClinicalTrials.gov/show/NCT00343603 Completed University of Pittsburgh 2010-12-31
NCT00342251 Investigating Age-Related Macular Degeneration https://ClinicalTrials.gov/show/NCT00342251 Completed National Institutes of Health Clinical Center (CC) NA
NCT00277784 High-Resolution Ultrasound Imaging of the Retina and Choroid for Detection on Age Related Macular Degeneration https://ClinicalTrials.gov/show/NCT00277784 Completed Weill Medical College of Cornell University 2006-06-30
NCT00797524 Function and Structure Imaging in Different Retinal Diseases: Retinal Leakage Analyzer Versus Optical Coherence Tomography https://ClinicalTrials.gov/show/NCT00797524 Completed Association for Innovation and Biomedical Research on Light and Image 2010-10-31
NCT00001395 Long Term Follow-Up of Diabetic Retinopathy https://ClinicalTrials.gov/show/NCT00001395 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001346 Diabetic Retinopathy and Visual Function Study https://ClinicalTrials.gov/show/NCT00001346 Completed National Institutes of Health Clinical Center (CC) NA
NCT00041444 Multi-Ethnic Study of Atherosclerosis (MESA) - Ancillary Eye Study https://ClinicalTrials.gov/show/NCT00041444 Completed University of Wisconsin, Madison 2006-11-30
NCT00001733 Screening for Studies on Retinovascular Diseases https://ClinicalTrials.gov/show/NCT00001733 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02435940 Inherited Retinal Degenerative Disease Registry https://ClinicalTrials.gov/show/NCT02435940 Recruiting Foundation Fighting Blindness 2037-06-30
NCT04128150 High Resolution Retina Imaging https://ClinicalTrials.gov/show/NCT04128150 Recruiting Centre Hospitalier National d’Ophtalmologie des Quinze-Vingts 2023-01-30
NCT04087356 Age-related Macular Degeneration (AMD) and Cardiovascular Disease https://ClinicalTrials.gov/show/NCT04087356 Recruiting The New York Eye & Ear Infirmary 2020-01-31
NCT03492853 The Association of the Peripheral Retinal Changes and Genotypic Changes in Patients With Age Related Macular Degeneration https://ClinicalTrials.gov/show/NCT03492853 Completed University Hospital “Sestre Milosrdnice” 2016-09-20